Sinnott-Armstrong Lab

Diurnal glucose GWAS

Time of day dependent glucose GWAS.

GWAS
3
Loci
4
Build
hg19

From Sinnott-Armstrong et al. 2026, Nature Communications

These GWAS were generated as part of (Sinnott-Armstrong et al., 2026).

Use Compare on any trait page to draw a Miami plot, or open a variant to see its PheWAS across all three traits.

Glucose interacted with sine of time of day Glycemic · 2 loci · top: MTNR1B
Glucose interacted with cosine of time of day Glycemic · 2 loci · top: MTNR1B
Glucose adjusted for time of day Glycemic · 1,770 loci · top: SPC25

Data sources

  • UK Biobank387,000 unrelated European-ancestry participants with measured glucose.

References

Sinnott-Armstrong, N., Strausz, S., Urpa, L., Abner, E., Johnson, J. P., Valliere, J., Palumaa, T., FinnGen, Team, E. B. R., Program, V. M. V.others. (2026). Genetic variants affect diurnal glucose levels throughout the day. Nature Communications. Lab paper Data