The genetic architecture of fibromyalgia across 2.5 million individuals

Multi-ancestry GWAS meta-analysis of fibromyalgia with 54K cases and 2.5M controls from 11 cohorts.

GWAS
5
Loci
26
Build
hg38

Preview. See paingenomics.org for genome-wide variant search.

From Kerrebijn et al. 2026, Nature Medicine

Genome-wide summary statistics for the fibromyalgia meta-analysis. The full-cohort, multi-ancestry result is the primary analysis. Also available are European-ancestry and sex-stratified GWAS.

All sumstats and polygenic risk scores from this study (Kerrebijn et al., 2026) are available on the Chronic Pain Genomics Consortium website and on Zenodo, including additional leave-each-cohort-out sumstats.

Polygenic risk scores

Data sources

References

Kerrebijn, I., Bjornsdottir, G., Arbabi, K., Urpa, L., Haapaniemi, H., Thorleifsson, G., Stefansdottir, L., Frangakis, S., Valliere, J., Kunorozva, L.others. (2026). The genetic architecture of fibromyalgia across 2.5 million individuals. Nature Medicine, 32, 3060–3070. Lab paper Data