Archive
Everything on this website in reverse-chronological order.
2026
- Congratulations to Isabel for a new publication in Nature Medicine! Posts
- Congratulations to Nasa for a new publication in Nature Communications! Posts
- Congratulations to Atia for being named a Mahan Fellow! Posts
- Lil Lab Network Projects
- GLAM Consortium Projects
- Genetic Epidemiology of ME/CFS (GEM) Consortium Projects
- Chronic Pain Genomics Consortium Projects
- Support the Lab
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- AI Policy
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- Blogging setup for accessible and archivable science Posts
- The genetic architecture of fibromyalgia across 2.5 million individuals Publications
- Pelvic and Inguinal Lymphadenopathy in a Murine Model of Lyme Disease: Is LD-Gynecological Pathology Immune-Mediated? 2257953 Publications
- Participatory-informed preference optimization (PiPrO): A reinforcement learning simulation study Publications
- Meta-analysis of Cannabis Use Identifies Shared Genetic Loci with Sleep and Circadian Rhythms Publications
- Large language model-based bibliometric evaluation of population descriptors in human genetics Publications
- Genetic variants affect diurnal glucose levels throughout the day Publications
- From Collection to Collaboration: Building Ethical Frameworks for Genetic Research Publications
- An emergent disease-associated motor neuron state precedes cell death in ALS Publications
2025
- Congratulations to Nasa for being named a Pew Biomedical Scholar! Posts
- Social Factors of Health Covary with Population Stratification and Confound Heritability Estimates Publications
- Protect transgender scientists Publications
- Lyme disease increases risk for multiple gynecological conditions Publications
- Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome Publications
- Genome-wide association study of long COVID Publications
- Framework for bias evaluation in large language models in healthcare settings Publications
- Examining the Effect of Social Determinants of Health on Human Trait Heritability Publications
- An emergent disease-associated motor neuron state precedes cell death in a mouse model of ALS Publications
2024
- Understanding genetic variants in context Publications
- Sleep inertia drives the association of evening chronotype with psychiatric disorders: epidemiological and genetic evidence Publications
- SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease Publications
- Revealing the 2300-Year-Old Fermented Beverage in a Bronze Bottle from Shaanxi, China Publications
- Queer-and trans-inclusive faculty hiring—A call for change Publications
- Nightmares share genetic risk factors with sleep and psychiatric traits Publications
- Genetic variants affect diurnal glucose levels throughout the day Publications
- Genetic and functional analysis of Raynaud’s syndrome implicates loci in vasculature and immunity Publications
- Addressing 6 challenges in generative AI for digital health: A scoping review Publications
2023
- SIRP\alpha controls CD47-dependent platelet clearance in mice and humans Publications
- Portability of Polygenic Risk Scores for Sleep Duration, Insomnia and Chronotype in 33,493 Individuals Publications
- Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy Publications
- Metabolomic epidemiology offers insights into disease aetiology Publications
- Genome-wide Association Study of Long COVID Publications
- Diversity of ribosomes at the level of rRNA variation associated with human health and disease Publications
- An epidemiological introduction to human metabolomic investigations Publications
- A non-coding variant linked to metabolic obesity with normal weight affects actin remodelling in subcutaneous adipocytes Publications
- A comprehensive rRNA variation atlas in health and disease Publications
2022
- Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks Publications
- Large-scale genome-wide association study of coronary artery disease in genetically diverse populations Publications
- Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation Publications
- Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits Publications
- A flexible modeling and inference framework for estimating variant effect sizes from GWAS summary statistics Publications
- A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs Publications
2021
- Tracing DNA paths and RNA profiles in cultured cells and tissues with ORCA Publications
- Sex-specific genetic effects across biomarkers Publications
- Scaling of SARS-CoV-2 RNA in Settled Solids from Multiple Wastewater Treatment Plants to Compare Incidence Rates of Laboratory-Confirmed COVID-19 in Their Sewersheds Publications
- p53 is a central regulator driving neurodegeneration caused by C9orf72 poly (PR) Publications
- GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background Publications
- Graphical analysis for phenome-wide causal discovery in genotyped population-scale biobanks Publications
- Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5 Publications
- Early Release-Performance of Nucleic Acid Amplification Tests for Detection of Severe Acute Respiratory Syndrome Coronavirus 2 in Prospectively Pooled Specimens Publications
- Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler Publications
- Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler Publications
- A regulatory variant at 3q21. 1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density Publications
- A large-scale multi-ethnic genome-wide association study of coronary artery disease Publications
- A genome-wide atlas of co-essential modules assigns function to uncharacterized genes Publications
2020
- SARS-CoV-2 RNA in wastewater settled solids is associated with COVID-19 cases in a large urban sewershed Publications
- Performance of Nucleic Acid Amplification Tests for Detection of Severe Acute Respiratory Syndrome Coronavirus 2 in Prospectively Pooled Specimens. Publications
- Pan-cancer analysis of whole genomes. Publications
- Multiomic blood correlates of genetic risk identify presymptomatic disease alterations Publications
- Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma Publications
- Long-range single-molecule mapping of chromatin accessibility in eukaryotes Publications
- Landscape of cohesin-mediated chromatin loops in the human genome Publications
- Evaluation of Group Testing for SARS-CoV-2 RNA Publications
- Dopaminergic stimulants and risk of Parkinson's disease Publications
- Convergent mutations in tissue-specific regulatory regions reveal novel cancer drivers Publications
- Chromatin accessibility dynamics in a model of human forebrain development Publications
- Analyses of non-coding somatic drivers in 2,658 cancer whole genomes Publications
- A microRNA linking human positive selection and metabolic disorders Publications
- A lead candidate functional single nucleotide polymorphism within the WARS2 gene associated with waist-hip-ratio does not alter RNA stability Publications
2019
- The origins of specialized pottery and diverse alcohol fermentation techniques in Early Neolithic China Publications
- Reduced signal for polygenic adaptation of height in UK Biobank Publications
- Opportunities and challenges for transcriptome-wide association studies Publications
- Nightmares share strong genetic risk with sleep and psychiatric disorders Publications
- Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration Publications
- Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study. Publications
- Genetics of 38 blood and urine biomarkers in the UK Biobank Publications
- Discovery of common and rare genetic risk variants for colorectal cancer Publications
- Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors Publications
2018
- Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells Publications
- Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival Publications
- Loss of LDAH associated with prostate cancer and hearing loss Publications
- High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human Publications
- Diff-seq: A high throughput sequencing-based mismatch detection assay for DNA variant enrichment and discovery Publications
2017
- Reports from CAGI: The critical assessment of genome interpretation Publications
- Predicting gene expression in massively parallel reporter assays: A comparative study Publications
- An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues Publications
2016
- Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer Publications
- Convergence of dispersed regulatory mutations predicts driver genes in prostate cancer Publications
- Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170 Publications
2015
2013
- Cell-Based Metrics Improve the Detection of Gene-Gene Interactions Using Multifactor Dimensionality Reduction. Publications
2012
- GAMETES: a fast, direct algorithm for generating pure, strict, epistatic models with random architectures Publications
- BioLite, a Lightweight Bioinformatics Framework with Automated Tracking of Diagnostics and Provenance. Publications
2011
- Random artificial incorporation of noise in a learning classifier system environment Publications
- Multiple assessments of local properties, production, and performance in metal objects: an experimental case study from Petra, Jordan Publications
- Characterizing genetic interactions in human disease association studies using statistical epistasis networks Publications
2010
- Wording effects in moral judgments Publications
- Multifactor dimensionality reduction for graphics processing units enables genome-wide testing of epistasis in sporadic ALS Publications
- High performance parallel disease detection: an artificial immune system for graphics processing units Publications
- Fast genome-wide epistasis analysis using ant colony optimization for multifactor dimensionality reduction analysis on graphics processing units Publications
- Exploiting graphics processing units for computational biology and bioinformatics Publications